該基因編碼絲氨酸蛋白酶的肽酶s1或糜蛋白酶家族的一個成員。編碼的前蛋白通過蛋白質水解產生輕鏈和重鏈，通過二硫鍵結合形成異二聚體酶。這種酶在前列腺上皮中高度表達，是在精液中發現的幾種蛋白水解酶之一。這種蛋白酶具有胰蛋白酶樣底物特異性，在賴氨酸或精氨酸殘基的羧基末端切割蛋白質底物。編碼的蛋白酶部分介導上皮鈉通道（鈉平衡的調節者）的蛋白水解酶激活，并可能在上皮屏障形成中發揮作用。[由RefSeq提供，2016年2月]
This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]