該基因編碼的蛋白是蛋白酪氨酸磷酸酶（PTP）家族的成員。PTP是調節多種細胞過程的信號分子，包括細胞生長、分化、有絲分裂周期和致癌轉化。這個ptp包含一個c-末端害蟲基序，作為一個蛋白質-蛋白質相互作用域，可以調節蛋白質的細胞內半衰期。這種PTP被發現與癌基因c-abl的產物結合并去磷酸化，因此可能在腫瘤發生中起作用。這種PTP還顯示與細胞骨架結構和細胞粘附相關的各種產物，如p130（cas）、cakbeta/ptk2b、pstpip1和paxillin相互作用和去磷酸化。這表明它在控制細胞形狀和流動性方面具有調節作用。選擇性剪接導致編碼不同亞型的多個轉錄變體。
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms.