該基因是一個鋅指轉錄因子小家族的成員，在脊椎動物發育過程中對細胞分化和器官發生起著重要的調控作用。該基因在早期胚胎發生過程中表達，并在后期胚胎發生過程中定位于內皮細胞和中胚層細胞，因此在腸、肺和心臟發育中發揮重要作用。這個基因的突變與一些先天性缺陷有關。[由RefSeq提供，2012年3月]
This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012]