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  • 發布時間:2022-09-06 15:18 原文鏈接: 實體腫瘤檢測NTHL1基因介紹

    這個基因編碼的蛋白質是一種核酸內切酶iii家族的dna n-糖基化酶。與大腸桿菌中的類似蛋白質一樣,編碼的蛋白質在含有氧化嘧啶殘基的dna底物上具有dna糖苷酶活性,并且具有無嘌呤/無嘧啶裂解酶活性。

    The protein encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. 

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