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  • 發布時間:2022-09-06 15:56 原文鏈接: 實體腫瘤檢測XRCC2基因介紹

    該基因編碼reca/rad51相關蛋白家族的一個成員,參與同源重組以維持染色體穩定性和修復dna損傷。該基因通過同源重組參與dna雙鏈斷裂的修復,并在功能上與中國倉鼠irs1互補,irs1是一種修復缺陷突變體,對多種不同的dna損傷劑表現出超敏反應。

    This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [

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