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  • 發布時間:2022-07-20 12:48 原文鏈接: 遺傳風險基因信號通路相關因子BRIP1

    該基因編碼的蛋白質是recq-deah螺旋酶家族的成員,與乳腺癌1型(brca1)的brct重復序列相互作用。結合復合體在1型乳腺癌(brca1)正常雙鏈斷裂修復功能中起重要作用。這個基因可能是生殖系癌癥誘發突變的靶點。[由RefSeq提供,2008年7月]
    The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq, Jul 2008]

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