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  • 發布時間:2022-08-08 19:22 原文鏈接: BAZ2B基因編碼功能及結構描述

    該基因屬于溴多胺基因家族這個基因家族的成員編碼的蛋白質是染色質重塑復合物的組成部分。在組蛋白肽篩選中,編碼的蛋白對激活的h3k14ac標記表現出強烈的偏好,這表明在轉錄激活中可能起到了作用。該基因可能與心臟性猝死(scd)易感性有關。[由RefSeq提供,2016年8月]

    This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

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