• <noscript id="yywya"><kbd id="yywya"></kbd></noscript>
  • 發布時間:2022-08-09 09:58 原文鏈接: CROT基因編碼功能及結構描述

    這個基因編碼肉堿/膽堿乙酰轉移酶家族的一個成員。編碼的蛋白質將4,8-二甲基壬酰基-CoA轉化為相應的肉堿酯這種酯交換反應發生在過氧化物酶體中,是將長鏈酰基-CoA分子從過氧化物酶體轉運到細胞質和線粒體所必需的。因此,蛋白質在脂質代謝和脂肪酸β氧化中起作用。已經描述了選擇性剪接的轉錄變體。[由refseq提供,2009年1月]

    This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]

  • <noscript id="yywya"><kbd id="yywya"></kbd></noscript>
  • 东京热 下载