這個基因編碼一個轉錄因子，它是堿性亮氨酸拉鏈（bzip）蛋白的一個小家族的成員。編碼的轉錄因子調節啟動子中含有抗氧化反應元件（are）的基因；其中許多基因編碼參與對損傷和炎癥反應的蛋白質，包括自由基的產生。編碼不同亞型的多個轉錄變體已經被鑒定為該基因。[由RefSeq提供，2015年9月]
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]