這個基因的產物屬于一個小的轉接器蛋白家族，已知它與許多受體酪氨酸激酶和信號分子相互作用。該基因編碼一種與表皮生長因子受體（EGFR）和腎上腺素受體相互作用的生長因子受體結合蛋白該蛋白通過與粘著斑激酶（FAK）結合在整合素信號通路和細胞遷移中發揮作用已經發現了編碼兩種不同亞型的轉錄變體[由RefSeq提供，2011年6月]
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]