m通道是一種緩慢激活和失活的鉀通道，在神經元興奮性的調節中起著關鍵作用。m通道是由該基因編碼的蛋白質和kcnq3基因編碼的相關蛋白質（兩者都是完整的膜蛋白）結合形成的。m通道電流被m1毒蕈堿乙酰膽堿受體抑制，并被新型抗驚厥藥物retigabine激活。該基因缺陷是1型良性家族性新生兒驚厥（BFNC）的病因，也稱為癲癇，1型良性新生兒驚厥（EBN1）該基因至少有5個轉錄變體，編碼5種不同的亞型。[由RefSeq提供，2008年7月]
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]