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  • 發布時間:2022-07-27 11:14 原文鏈接: KITLG基因突變與藥物因子介紹

    該基因編碼KIT位點編碼的酪氨酸激酶受體配體這種配體是一種多效性因子,在子宮生殖細胞、神經細胞發育和造血中起作用,所有這些都被認為反映了細胞遷移的作用在成人中,它的功能是多方面的,而主要是以它在造血方面的持續需求而聞名。已經發現了兩個編碼不同亞型的轉錄變體。[由RefSeq提供,2008年7月]
    This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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