一氧化氮是一種反應性自由基，在多種過程中起著生物調節劑的作用，包括神經傳遞、抗菌和抗腫瘤活性。該基因編碼在肝臟中表達的一氧化氮合酶，并通過脂多糖和某些細胞因子的組合誘導。三個相關的假基因位于17號染色體的Smith-Magenis綜合征區域內。[由RefSeq提供，2008年7月]
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]