多形性腺瘤基因1編碼鋅指蛋白和2個假定的核定位信號。plag1是一種發育調控因子，在涎腺多形性腺瘤中被一致地重新排列。plag1被唾液腺多形性腺瘤中涉及8q12的相互染色體易位激活。已經發現了三個編碼兩種不同亞型的轉錄變體。
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.