這個基因編碼一個組蛋白甲基轉移酶，它調節組蛋白甲基化、基因沉默和轉錄抑制。鑒于基因沉默和轉錄功能障礙可能在亨廷頓病的發病機制中起作用，該基因已被確定為亨廷頓病治療的靶點已經描述了該基因的選擇性剪接轉錄變體。[由RefSeq提供，2011年6月]
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]