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  • 發布時間:2022-08-23 09:48 原文鏈接: SUZ12基因編碼的功能和結構描述

    這個鋅指基因在子宮內膜間質肉瘤中一個復發性染色體易位的斷點被發現。這些斷裂點的重組導致該基因與jazf1融合。這個基因編碼的蛋白質在編碼區的C端含有一個鋅指結構域。

    This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. 

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