真核細胞骨架的微管具有多種功能，由α和β微管蛋白的異二聚體組成。編碼這些微管成分的基因是微管蛋白超家族的一部分，該家族由六個不同的家族組成。所有真核生物中都有α、β和γ微管蛋白家族的基因。α和β微管蛋白是微管的主要成分，而γ微管蛋白在微管組裝成核過程中起著關鍵作用有多種α和β-微管蛋白基因，在種間和種間高度保守。該基因是一個α-微管蛋白基因，編碼一種與小鼠睪丸特異性Tuba3和Tuba7基因產物99%相同的蛋白質該基因位于13q11區，與多汗性外胚層發育不良和歌舞伎綜合征等遺傳病有關[由RefSeq提供，2008年7月]
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008]