該基因屬于TIS11家族的早期反應基因，由多種激動劑如佛波酯TPA和多肽絲裂原EGF誘導這個基因在不同物種間都很保守，并且有一個啟動子，包含在其他早期反應基因中看到的基序。編碼蛋白包含一個具有重復cys-his基序的鋅指區。這種假定的核轉錄因子很可能在調節對生長因子的反應中發揮作用另外，已經發現該基因編碼不同亞型的剪接轉錄變體[由RefSeq提供，2011年9月]
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]