該基因是TIS11早期反應基因家族的成員家族成員是由不同的激動劑如佛波酯tpa和多肽絲裂原egf誘導的。編碼蛋白包含一個具有重復cys-his基序的鋅指區。這種假定的核轉錄因子很可能在調節對生長因子的反應中發揮作用。
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.