該基因是一種腫瘤抑制因子，編碼一種與真核細胞翻譯起始因子4A1結合并通過阻止RNA結合抑制其功能的蛋白質。選擇性剪接導致多個轉錄變體。
This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants.