Interleukin6InducedAcutePhenotypicMicroenvironmentPromote...（三）
Target analysis by Parallel reaction monitoring (PRM)The targeted quantification and verification were carried out in 94 serum samples with 5~6 mice in each condition without pooling, across 8 time points. 23 proteins were selected with 1~4 peptides, resulting in 33 precursors in total (Additional File 1: Table S1). Glycopeptides were enriched as above and one of the angiotensin peptides was spiked in......閱讀全文
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（三）
?Target analysis by Parallel reaction monitoring (PRM)The targeted quantification and verification were carried out in 94 serum samples with 5~6 mic
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（八）
In summary, we suggested that “acute” response could elicit innate and Th1 adaptive immunity, reversing the tumor-mediated immunosuppressive envi
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（十）
In this study, we found that “acute” response was strongly induced by cryo-thermal therapy with “acute” and high expression of a series of acute
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（七）
Figure 7. The expression of three acute phase proteins after IL-6 neutralization. Mice were injected intraperitoneally with mouse anti-IL-6 Ab 3 and
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（五）
??Figure 2. Proteomics analysis of serum glycoproteins from treated and untreated mice. 21 days after cell injection, mice underwent cryo-thermal or
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（六）
Cryo-thermal therapy induced an “acute” phase response?First, we performed PRM analysis upon significant proteins involved in acute phase response,
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（一）
Interleukin-6 Induced Acute Phenotypic Microenvironment Promotes Th1 Anti-Tumor ImmunityTing Xue1, Ping Liu1, Yong Zhou2, Kun Liu1, Li Yang2, Robert L
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（九）
The strongest and unique “acute” environment induced by cryo-thermal therapy stimulated the most effective anti-tumor immune response?As described
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（二）
As a primary component of circulatory system, serum is the major reservoir of thousands of proteins secreted or “leaked” from a broad spectrum of
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（四）
Flow cytometrySpleens were extracted after therapy and mechanically homogenized with gentle MACS Dissociator to obtain a single-cell splenocyte su
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Prom...（十一）
Conclusion In summary, using comprehensive discovery proteomics analysis followed by target proteomics validation at a large scale sample size,
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Prom...（十二）
References1. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA: a cancer journal for clinician
Developmental－and－phenotypic－implications－of－transplantation
ObjectiveIn this experiment, a region of the neural crest will be transplanted from one stage-fourteen embryo to another (Figure 1). To facilitate the
Free－Radical－Induced－Apoptosis
Oxidative stress is one factor that can trigger programmed cell death. Activated neutrophils responding to inflammatory stimulation produce reactive o
Lectin－Induced－Complement－Pathway
The complement cascade of proteolytic factors involved in cellular lysis can be initiated by several different factors, including antibody-dependent a
Chloroplast－Phenomics:－Systematic－Phenotypic－Screening－of－Chloroplast－...
Chloroplast Phenomics: Systematic Phenotypic Screening of Chloroplast Protein Mutants in Arabidopsis As part of a project to analyze chloroplast fun
Bioactive－Peptide－Induced－Signaling－Pathway
Many different peptides act as signaling molecules, including the proinflammatory peptide bradykinin, the protease enzyme thrombin, and the blood pres
HIV－Induced－T－Cell－Apoptosis
HIV infection is associated with immunosuppression caused by a dramatic reduction in the helper T cell population. The loss of helper T cells may be c
Cells－and－Molecules－involved－in－local－acute－inflammatory－response
Inflammation has several distinct components, including the localized response at the site of tissue injury or infection. Tissue injury stimulates the
Double－Stranded－RNA－Induced－Gene－Expression
One defense against viral infection is provided by PKR, double-stranded RNA activated protein kinase. When PKR interacts with dsRNA found in cells dur
Cytokine－induced－angiogenesis－in－chick－embryos.
Objective:The purpose of this experiment was to explore the effects of the growth factors bFGF and VEGF on blood vessel formation within the chorioall
TSP1－Induced－Apoptosis－in－Microvascular－Endothelial－Cell
As tissues grow they require angiogenesis to occur if they are to be supplied with blood vessels and survive. Factors that inhibit angiogenesis might
CBL－mediated－ligandinduced－downregulation－of－EGF－receptors
As with many cell-surface receptors, activation of the EGF receptor can result in receptor internalization through receptor-mediated endocytosis, dese
siRNAs結合生物芯片的實驗設計1
Ambion and Applied Biosystems have joined forces to provide a complete convenient, solution for performing gene silencing experiments and validating
fMLP－induced－chemokine－gene－expression－in－HMC1－cells
Neutrophils respond to bacterial infection by releasing reactive oxygen species that kill bacteria and by expressing chemokines that attract other imm
Oxidative－Stress－Induced－Gene－Expression－Via－Nrf2
Reactive oxygen species (ROS) can damage biological macromolecules and are detrimental to cellular health. Electrophilic compounds, xenobiotics and an
Dynamic－Monitoring－ofCellular－Remodeling－Induced－bythe－Transforming－Growth1
The plasticity of differentiated adult cells could have a great therapeutic potential, but at the same time, it is characteristic of progression of se
Dynamic－Monitoring－ofCellular－Remodeling－Induced－bythe－Transforming－Growth2
Results and discussionData acquisition demonstrated a linear increasing of the CI values in control cells during the time interval observed. However,
RNAinduced－initiation－of－transcriptional－gene－silencing（RITS）的用途
RNA-induced initiation of transcriptional gene silencing（RITS）：是一種組織染色質變型的復合物。RITS復合物也包含Dicer加工形成的siRNA和AGO蛋白質，通過結合到異染色質的基因池上來促使異染色質上基因的沉默。
Dynamic－Monitoring－ofCellular－Remodeling－Induced－bythe－Transforming－Growth2
Results and discussionData acquisition demonstrated a linear increasing of the CI values in control cells during the time interval observed. However,